The “Slings and Arrows of a Disease: Parkinson"Medical Park International Created: 2016-06-15 09:35:03
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The “Slings and Arrows of a Disease: Parkinson"

Parkinson’s disease, the nightmare of elderly subjects, is a chronic neurological disease which is secondary to decreased level of a substance, namely dopamine, in brain. The disease results from decrease or injury of cerebral cells, which secrete dopamine, secondary to aging.

The “Slings and Arrows of a Disease: Parkinson"

Parkinson’s disease, also known as “disease of elderly” and colloquially known as “shaky stroke”, is no more an untreatable condition, thanks to the options of medications and neurostimulator (a small battery-powered device). Stating that Parkinson’s disease is a chronic disorder and the incidence is 1/300 for people aged ≥65 years, Neurosurgery Deaprtment of Medical Park Hospitals Group, Turkey informed us about the nightmare of elderly people, the Parkinson’s disease:

What is Parkinson’s disease?

Parkinson’s disease is a chronic neurological disease which is secondary to decreased level of a substance, namely dopamine, in brain. Resulting from decrease or injury of dopamine-releasing cells of brain secondary to aging, the disease leads to movement disorders and involuntary movements. The disease is usually manifested by tremor in hands and feet, slowness of movement, rigidity and gait instability.


Parkinson’s disease is associated with slowness of movements (bradykinesia), resulting with inability to do jobs independently followed by dependence to others in routine daily activities. Therefore, patients isolates themselves from business and social life at baseline and intermediate phases of the disease, while they should have support of others to survive at advanced stage. Those problems lead to adverse effects on emotional health, introversion or depression in patients who are already suffering from slowness of movements and tremor.


The aim of “Micro-electrode Recording and Stimulation Technique”, which enables us “listening to” electrical activity of single neuron (brain cell), is to identify cells involved in the process and anatomic structures surrounding the involved cell. For this purpose, patient should be awake during surgery and we talk with the patient intraoperatively. We advance an electrode, with a two-micron thick tip, into brain under guidance of computer and the electrode is connected to complex circuits; thus, we can listen to electrical activity of a single neuron or we can observe response of patient to low-current stimulations. Accordingly, we measure response of patient and it is easier to reach or identify the region involved. Patient is awake within first 3-4 hours of surgery and we cooperate with the patient and vice versa. This technology, namely “Micro-electrode Recording and Stimulation Technique”, makes us achieve our aim. Thanks to this system which is associated with an error rate of 80 microns, we can identify neurons involved and anatomic structures surrounding those neurons. Next, we apply laser method, which is somewhat like burning the lesion, and the neurostimulator is implanted.


Considering implantation of neurostimulator, we place two electrodes to regions involved in bilateral surgery. A battery, similar to pace maker, is placed into subcutaneous layer on chest wall and extension wires are advanced through subcutaneous layer and thus, electrodes are connected to the battery. The system is not visible. You may see or feel a bulging (or swelling) on chest wall. Next, we adjust frequencies and stimulation parameters, which are beneficial for patient, using a computer system. Patient should return to clinic frequently within postoperative 2-3 weeks. Normal daily life activities can be resumed after optimum adjustments are made. Patients will have impressive improvement and they may return to normal daily life in postoperative period.


What kind of a change is induced by neurostimulator in daily life of patients?

Patients with Parkinson’s disease will have impressive improvement and they may return to normal daily life in postoperative period. Neurostimulation creates a link to normal daily life for patients. After necessary battery parameters are adjusted in the postoperative period, patients, who may not event hold fork, thread a needle or write, may enjoy old healthy days. Suffering from inability to tie shoe lace, button up shirt and live without support of a caregiver, resulting with social isolation, patients will have the chance to live an independent life and return to ordinary work life after neurostimulator is implanted.


A successful surgery may set the biological back to first or second year of the condition in a patient, who has been suffering from Parkinson’s disease for 10 years, if correct patient is selected. It is possible to completely eliminate tremor at least in single hand (right or left half of body) at rate of 85-90 percent. Although there is inter-patient variation, the clinical improvement rate is around 80% in patients with dystonia, or in other words, no response can be observed in up to 20% of patients with dystonia.


65% of the international patients dignosed Parkinson travel Turkey from the Gulf region to undergone ‘Implant of Neurostimulation for Parkinson’s disease’ in Medical Park Hospitals Group.

Medical Park Hospitals Group, one of the leading player in the sector, makes a major progress in medical tourism during the recent years and started to have a great number of treatment demands from international patients all around the world including Middle East.

Medical Park attracts highest number of international patients by offering complete service for its international patients from coming to Turkey till returning back to their countries by caring with every detail such as their transportation, transfers, accommodation, guidance to treatment and medications.

For detailed information:

Medical Park Hospitals Group

International Patient Center

+90 212 227 11 00

+90 212 227 21 16

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