Learn about cornea transplant surgery, its types, what to expect during recovery, and potential risks.
Vision loss due to corneal issues is a significant cause of morbidity worldwide. A corneal transplant is a life-altering surgery that gives hope to patients suffering from low vision or complete vision loss due to corneal damage and pathologies.
According to ECCTR (European Cornea and Cell-transplantation Registry), the cornea is the most commonly transplanted intact tissue worldwide, with over 180,000 procedures annually.
Understanding Cornea Transplant
A cornea transplant is an eye surgery in which a donor cornea is transplanted to replace a diseased/damaged cornea for vision restoration. It is also known as Keratoplasty. The growth of medical tourism allows patients to receive corneal transplants in Turkey with ease and affordability to enhance their quality of life.
What is a Cornea?
The clear, dome-shaped surface in the front of the eye is known as the cornea. It protects the inner part of the eye and focuses the light rays on the retina as they pass through it. Corneal transparency is essential for clear vision. Disruption in the cornea anatomy may lead to permanent vision impairment.
Why is a Cornea Transplant Performed?
The main reason for a corneal transplant is to improve blurred vision or restore vision, relieve eye pain or discomfort, and treat severe infection/injury.
Conditions That May Require a Cornea Transplant
The common causes that lead patients to seek a corneal transplant are as follows:
- Traumatic damage
- Corneal diseases
- Corneal infections
- Corneal dystrophy
- Damaged cornea
Types of Cornea Transplant Surgery
The cornea transplant types available to patients are as follows:
Full-Thickness Cornea Transplant (Penetrating Keratoplasty)
Suitable for advanced/severe corneal damage, a penetrating keratoplasty replaces all the layers of the cornea with an intact donor cornea.
Partial-Thickness Cornea Transplants
This type of keratoplasty only replaces the diseased layers of the cornea with donor tissue. The advantages are faster healing and fewer complications.
Endothelial Keratoplasty (DSEK and DMEK)
An endothelial keratoplasty is a highly sought-after corneal transplant surgery in Turkey, with two main types. The first type is DSEK, also known as Descemet Stripping Endothelial Keratoplasty. The other is Descemet Membrane Endothelial Keratoplasty (DMEK).
An endothelial keratoplasty only focuses on the innermost (endothelial) layer of the cornea. A DSEK procedure is mostly performed to treat endothelial disorders and replaces the endothelium and some supporting tissue. Whereas, a DMEK replaces both the endothelium and Descemet’s membrane.
Anterior Lamellar Keratoplasty (ALK, SALK, and DALK)
Many patients get an anterior lamellar keratoplasty (ALK) in Istanbul every year. The procedure replaces all the layers of the cornea except the endothelium. It is classified as SALK (Superior Lamellar Keratoplasty) and DALK (Deep Anterior Lamellar Keratoplasty).
Preparing for Your Cornea Transplant
If you are planning a cornea transplant in Turkey, preparation is just as important as the recovery process. Following the recommended steps before surgery can help ensure a safer procedure and better results.
Pre-operative Assessments
Pre-operative assessments usually include detailed ocular exams, ocular imaging tests (OCT, Corneal topography, etc.), IOP (Intraocular pressure), and taking medical history of a patient about their secondary health issues.
Understanding the Donor Cornea Process
A cornea transplant offers a renewed chance at clear vision, but it’s essential to understand the process and its considerations. In Turkey, donor corneas are sourced from certified local eye banks that follow strict quality and safety standards. Learning about the donor tissue process, potential risks, and recovery expectations can help you feel more confident and prepared for the journey ahead.
What Happens During a Cornea Transplant?
A cornea transplant involves several steps to ensure the procedure is safe and effective.
Anesthesia Options
Your surgeon will choose the most suitable anesthesia based on your age, health, and comfort level. Most patients receive local anesthesia with sedation, which numbs the eye while keeping you relaxed. In some cases, such as with children, patients with tremors, or those experiencing high anxiety, general anesthesia may be recommended. If general anesthesia is used, you may need to stay at the hospital for a few hours after surgery for monitoring.
The Surgical Procedure
Once the eye is numb, the surgeon carefully removes the damaged corneal tissue, either partially or completely, and replaces it with healthy donor tissue. The new cornea is then secured in place with fine sutures, and an eye shield or protective bandage is applied to aid healing and prevent injury.
Recovery After Cornea Transplant Surgery
The recovery period after a corneal transplant is just as important as the surgery itself. Full visual recovery can take 6 to 12 months, and following your doctor’s instructions is key to a successful outcome.
Immediate Post-Operative Care
Right after your cornea transplant in Turkey, you’ll need to follow specific care guidelines to protect your eye and promote healing:
- Wearing an eye shield, especially during sleep
- Strict adherence to medication
- Attending all follow-up appointments
- Avoid rubbing the eye
- Avoid bending/lifting
Managing Pain and Discomfort
Mild pain and discomfort are managed with cold compresses and pain medication prescribed by the ophthalmologist.
Eye Drops and Medications
Antibiotic and steroid eye drops are prescribed after a corneal transplant in Turkey to prevent infection and ensure proper healing.
Stitches and Follow-Up Appointments
The stitch removal is gradual and over the course of months, so adhering to the follow-up appointments are important.
Vision Improvement Timeline
The vision stabilizes after 6 to 12 months of surgery. However, a full recovery may take up to 18 months.
Returning to Daily Activities
As per international guidelines, corneal transplant patients in Turkey are advised to avoid strenuous activities for several weeks. Patients return to light daily activities within a few days.
Potential Risks and Complications of Cornea Transplant
Corneal transplantation is generally a safe and effective way to restore vision. However, like any surgery, it carries certain risks. Being aware of these potential corneal complications can help you take preventive steps and seek timely care if needed.
General Surgical Risks
Some risks are common to most surgical procedures, including:
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Reactions to anesthesia
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Infection at the surgical site
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Bleeding during or after surgery
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Delayed healing, which can prolong recovery
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Swelling in or around the eye
Cornea Rejection: Symptoms and Management
One of the most devastating cornea complications after a transplant is donor cornea rejection. Signs may include red eyes, watering, pain, light sensitivity, and decreased vision. Early management with steroid eye drops has a good prognosis.
Other Possible Complications
Other possible cornea-transplant complications include raised intraocular pressure (Glaucoma), cataracts, and detached retina.
Living with Your New Cornea
Adjusting to life after a cornea transplant is a gradual process that requires patience, regular follow-ups, and a commitment to eye care. Vision improvement does not happen overnight. Many patients notice gradual changes over several months, and full recovery can take up to one year. During this time, your doctor will monitor your healing and adjust medications as needed.
Long-Term Care and Monitoring
Long-term care and monitoring for living with a new cornea require regular follow-up appointments and adherence to eye drops.
Importance of Adhering to Medical Advice
After a corneal transplant in Turkey, your doctor will give you relevant instructions on graft survival and treatment success. Following it diligently will give you the best chance of success.
For more information about comprehensive eye care services offered at MedicalPark hospitals, visit our Ophthalmology department page.
This content was developed by the MedicalPark Editorial Board and is intended for informational purposes only. It does not replace professional medical advice, diagnosis, or treatment. Please consult your healthcare provider for personalized care.

